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They have rejected the word of the Lord - It became in the hands of the Soferim or scribes a mere code of ceremonial observance. Compare ([R…

They have rejected the word of the Lord. —The “wise men” are apparently distinguished from the scribes, probably as stude…

How do ye say, We are wise, and the law of the LORD is with us? Lo, certainly in vain made he it; the pen of the scribes is in vain.
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He says now that the wise were ashamed, and astonished, and ensnared. By these words he means that the Jews gained nothing by their crafti…

The wise men are ashamed Of the wisdom of which they boasted, when it would appear to be folly, and unprofitable to them:…

What brought this ruin?

Here, he shows their pride, which stems from their boast of wisdom; concerning this, there are three things.
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Albert Barnes
AlbertBarnes