Or, “Perverse is the way of a sin-burdened man.”

The way of man is froward and strange— These words may also mean, “Tortuous is the way of a man who is laden with sin.” .

The way of man [is] froward and strange
Not the way of any and every man; not the way of righteous and good men, of …

The way of mankind by nature is perverse and strange.