Albert Barnes Commentary 1 Corinthians 16:21

"The salutation of me Paul with mine own hand." — 1 Corinthians 16:21 (ASV)

The salutation of me Paul with mine own hand. It is evident that Paul was accustomed to employ an amanuensis in writing his epistles (see Barnes on Romans 16:22).

Though he signed his own name and expressed his Christian salutation in every epistle (2 Thessalonians 3:17; Colossians 4:18), this validated what was written, was a proof that it was his own, and was a valuable token of affectionate regard. It was a proof that there was no fraud or imposition. Why he employed an amanuensis is not known.