Albert Barnes Commentary Acts 16:7

"and when they were come over against Mysia, they assayed to go into Bithynia; and the Spirit of Jesus suffered them not;" — Acts 16:7 (ASV)

Mysia. This was a province of Asia Minor, having Propontis on the north, Bithynia on the east, Lydia on the south, and the Aegean Sea on the west.

They assayed. They endeavored; they attempted.

Into Bithynia. A province of Asia Minor, lying east of Mysia.

Assayed. Attempted.