Albert Barnes Commentary Acts 22:21

"And he said unto me, Depart: for I will send thee forth far hence unto the Gentiles." — Acts 22:21 (ASV)

And he said to me, Depart. Because the Christians at Jerusalem would not receive him.

Far hence. Paul traveled far in the heathen nations. A large part of his time in the ministry was spent in remote countries, and in the most distant regions then known (Romans 15:19).