Albert Barnes Commentary Amos 2:5

"but I will send a fire upon Judah, and it shall devour the palaces of Jerusalem." — Amos 2:5 (ASV)

I will send a fire upon Judah - All know now how Jerusalem, its temple, and its palaces perished by fire, first by Nebuchadnezzar, then by the Romans. Yet some two centuries passed before that first destruction came. The ungodly Jews flattered themselves that it would never come. So we know that a fiery stream (Daniel 7:10) will issue and come forth from Him; a fire that consumeth to destruction (Job 31:12), all who, whether or not they are in the body of the Church, are not of the heavenly Jerusalem; dead members in the body which belongs to the Living Head.

And it will not come any less because it is not regarded. Rather, the very condition of all God’s judgments is to be disregarded and to come, and then all the more to come when they are most disregarded.