Albert Barnes Commentary Exodus 4:24

"And it came to pass on the way at the lodging-place, that Jehovah met him, and sought to kill him." — Exodus 4:24 (ASV)

In the inn - Or “resting place.” See (Genesis 42:27) note.

Met him, and sought to kill him - Moses was attacked by a sudden and dangerous illness, which he knew was inflicted by God. The word “sought to kill” implies that the sickness, whatever its nature, was one that threatened death had it not been averted by a timely act. Zipporah believed that the illness of Moses was due to his having neglected the duty of an Israelite, and to his not having circumcised his own son; the delay was probably owing to her own not unnatural repugnance to a rite, which, though practiced by the Egyptians, was not adopted generally in the East, even by the descendants of Abraham and Keturah. Moses appears to have been utterly prostrate and unable to perform the rite himself.