Albert Barnes Commentary Isaiah 17:1

"The burden of Damascus. Behold, Damascus is taken away from being a city, and it shall be a ruinous heap." — Isaiah 17:1 (ASV)

The burden of Damascus - The oracle indicating calamity or destruction to Damascus (see the note at Isaiah 13:1). “Damascus is taken away.” That is, it shall be destroyed. It was represented to the prophet in vision as destroyed (see the note at Isaiah 1:1).

And it shall be a ruinous heap - See Isaiah 35:2. This took place under the kings of Assyria, and particularly under Tiglath-pileser. This was in the fourth year of Ahaz (2 Kings 16:9).