Albert Barnes Commentary Isaiah 17:7

"In that day shall men look unto their Maker, and their eyes shall have respect to the Holy One of Israel." — Isaiah 17:7 (ASV)

At that day shall a man look to his Maker - Instead of relying on their strongly fortified places and armies, they will look for aid and protection to the God that made them, and who alone can help them. National afflictions and judgments often have the effect of turning the eyes of even a wicked and rebellious people to God. They feel their danger; they are convinced of their guilt; they see that no one but God can protect them; and for a time they are willing, even by humiliation and fasting, to seek the divine protection.

His eyes shall have respect... - He will look up to, or regard.

The Holy One of Israel - The God of Israel; the true God. As the Syrians were allied with the kingdom of Samaria or Ephraim, they were, of course, acquainted with the true God, and in some sense acknowledged him. In these times of impending calamity, they would be led to seek him, and implore his aid and protection. There is no reason to believe, however, that they would turn permanently to him, or become his true worshippers.