Albert Barnes Commentary Isaiah 19:16

"In that day shall the Egyptians be like unto women; and they shall tremble and fear because of the shaking of the hand of Jehovah of hosts, which he shaketh over them." — Isaiah 19:16 (ASV)

In that day shall Egypt be like unto women - Timid; fearful; alarmed. The Hebrews often, by this comparison, express great fear and consternation (Jeremiah 51:30; Nahum 3:13).

Because of the shaking of the hand - The shaking of the hand is an indication of threatening or punishment (note, Isaiah 10:32; Isaiah 11:15).