Albert Barnes Commentary Jeremiah 50:26

"Come against her from the utmost border; open her store-houses; cast her up as heaps, and destroy her utterly; let nothing of her be left." — Jeremiah 50:26 (ASV)

Against her - Or, to her, in order to plunder her. Her storehouses (literally granaries) are to burst open, the grain piled up in heaps, and finally they are to devote her to destruction, that is, to burn her wealth with fire.

From the utmost border - (Or, “from the first of you even to the last”).

Let nothing of her be left - literally, let her have no remnant. Contrast Jeremiah 5:10.