Albert Barnes Commentary Jeremiah 50:41-43

"Behold, a people cometh from the north; and a great nation and many kings shall be stirred up from the uttermost parts of the earth. They lay hold on bow and spear; they are cruel, and have no mercy; their voice roareth like the sea; and they ride upon horses, every one set in array, as a man to the battle, against thee, O daughter of Babylon. The king of Babylon hath heard the tidings of them, and his hands wax feeble: anguish hath taken hold of him, [and] pangs as of a woman in travail." — Jeremiah 50:41-43 (ASV)

(Jeremiah 50:41)

An application to Babylon of the doom against Jerusalem (Jeremiah 6:22–24).

The coasts of the earth - See the (Jeremiah 6:22) note.