Albert Barnes Commentary Job 16:7

"But now he hath made me weary: Thou hast made desolate all my company." — Job 16:7 (ASV)

But now he has made me weary — That is, God has exhausted my strength. This verse introduces a new description of his sufferings; and he begins with a statement of the woes that God had brought on him. The first was that he had taken away all his strength.

All my company — The word rendered “company” (עדה ‛êdâh) means properly an assembly that comes together by appointment, or at stated times; but here it is evidently used in the sense of the little community of which Job was the head and father. The sense is that all his family had been destroyed.