Albert Barnes Commentary Job 27:22

"For [God] shall hurl at him, and not spare: He would fain flee out of his hand." — Job 27:22 (ASV)

For God shall cast upon him – That is, God shall bring calamities upon him, or cast his thunderbolts upon him, and shall not pity him.

He would fain flee – He would gladly escape from the wrath of God, but he is unable to do it.