Albert Barnes Commentary Lamentations 1:17

"Zion spreadeth forth her hands; there is none to comfort her; Jehovah hath commanded concerning Jacob, that they that are round about him should be his adversaries: Jerusalem is among them as an unclean thing." — Lamentations 1:17 (ASV)

Spreadeth forth her hands - In prayer (Exodus 9:29, Exodus 9:33), but Zion entreats in vain. There is no one to comfort her—not God, for He is chastising her, nor man, for all the neighboring nations have become her enemies. See Lamentations 1:2.

That his adversaries ... - Rather, that those around him should be his adversaries; all the neighboring states should regard him with aversion.

Jerusalem is ... - that is, has become an abomination. The words are virtually the same as in Lamentations 1:8.