Albert Barnes Commentary Luke 1:25

"Thus hath the Lord done unto me in the days wherein he looked upon [me], to take away my reproach among men." — Luke 1:25 (ASV)

Thus. In this merciful manner.

To take away my reproach. Among the Jews, a family of children was counted a signal blessing, an evidence of the favour of God (Psalms 113:9; Psalms 128:3; Isaiah 4:1; Isaiah 44:3–4; Leviticus 26:9).

To be barren, therefore, or to be destitute of children, was considered a reproach or a disgrace (1 Samuel 1:6).