Albert Barnes Commentary Numbers 13:22

"And they went up by the South, and came unto Hebron; and Ahiman, Sheshai, and Talmai, the children of Anak, were there. (Now Hebron was built seven years before Zoan in Egypt.)" — Numbers 13:22 (ASV)

The ancestor of the Anakim was Arba "the father of Anak" (Joshua 15:13), from whom the city of Hebron took its name of Kirjath-Arba. Ahiman, Sheshai, and Talmai were probably not individual warriors, but names of three tribes of the Anakim. Therefore, we find them still in existence half a century later, when Caleb, who now reported on them, became their eventual destroyer (Joshua 15:14).

Now Hebron ... - This parenthesis explains that these two cities had a common founder, and were built, or perhaps, at least in the case of Zoan (Tanis, see Exodus 1:8, note; Exodus 2:5, note) rebuilt by the Hyksos, to which people, once the conquerors of Egypt, the Anakim perhaps belonged. The Hyksos fortified and garrisoned Zoan as a defense of their Eastern frontier.