Albert Barnes Commentary Psalms 69:24

"Pour out thine indignation upon them, And let the fierceness of thine anger overtake them." — Psalms 69:24 (ASV)

Pour out thine indignation upon them - That is, Punish them for their sins; or, do justice to them.

And let thy wrathful anger - literally, “the burning of your wrath;” glow of anger; burning wrath. See (Numbers 25:4); (Numbers 32:14), (1 Samuel 28:18). This is undoubtedly a petition that God would visit them with the severity of his indignation; or, it expresses the belief of the psalmist that they “deserved” such tokens of his displeasure.

Take hold of them - Seize upon them; overtake them when they expect to escape.