Albert Barnes Commentary Psalms 69:3

"I am weary with my crying; my throat is dried: Mine eyes fail while I wait for my God." — Psalms 69:3 (ASV)

I am weary of my crying - The word crying here does not mean weeping, or shedding tears, but calling upon God for help. He had grown weary; his strength had been exhausted in the act of calling upon God to assist him. See the notes at (Psalms 6:6). This was an instance where one had called so long on God, and prayed so much and so earnestly, that his strength was gone. Compare (Matthew 26:41).

My throat is dried - Or, is parched up. The Hebrew word denotes to burn; to be enkindled; and then, to be inflamed. Here it means that by the excessive exertion of his voice, his throat had become parched, so that he could not speak.

My eyes fail - That is, become dim from exhaustion. I have looked so long in that one direction that the power of vision begins to fail, and I see nothing clearly. See the notes at (Psalms 6:7). Compare (Job 17:7; Psalms 31:9; Psalms 38:10).

While I wait for my God - That is, by continued looking to God. The word wait is not used here, nor is it generally in the Bible, as it is now with us, in the sense of looking for future interposition, or of doing nothing ourselves in expectation of what may occur; but it is used in the sense of looking to God alone; of exercising dependence on him; of seeking his aid. This is indeed connected with the ordinary idea of abiding his will, but it is also an active state of mind - a state expressive of intense interest and desire. See the notes at (Psalms 62:5).