A.T. Robertson Commentary 2 Corinthians 12:8

"Concerning this thing I besought the Lord thrice, that it might depart from me." — 2 Corinthians 12:8 (ASV)

Concerning this thing (υπερ τουτου). More likely, "concerning this messenger of Satan."

That it might depart from me (ινα αποστη αφ' εμου). Second aorist active (intransitive) subjunctive of αφιστημ in final clause, "that he stand off from me for good."