A.T. Robertson Commentary Ephesians 6:18

"with all prayer and supplication praying at all seasons in the Spirit, and watching thereunto in all perseverance and supplication for all the saints," — Ephesians 6:18 (ASV)

At all seasons (εν παντ καιρω). "On every occasion." Prayer is needed in this fight. The panoply of God is necessary, but so is prayer. "Satan trembles when he sees The weakest saint upon his knees."