A.T. Robertson Commentary John 4:54

"This is again the second sign that Jesus did, having come out of Judaea into Galilee." — John 4:54 (ASV)

The second sign that (δευτερον σημειον). No article, simply predicate accusative, "This again a second sign did Jesus having come out of Judea into Galilee." The first one was also in Cana (2:1ff.), but many were wrought in Jerusalem also (2:23).