A.T. Robertson Commentary Luke 11:49

"Therefore also said the wisdom of God, I will send unto them prophets and apostles; and [some] of them they shall kill and persecute;" — Luke 11:49 (ASV)

The wisdom of God (η σοφια του θεου). In Mt 23:34 Jesus uses "I send" (εγω αποστελλω) without this phrase "the wisdom of God." There is no book to which it can refer. Jesus is the wisdom of God as Paul shows (1 Corinthians 1:30), but it is hardly likely that he so describes himself here. Probably he means that God in his wisdom said, but even so "Jesus here speaks with confident knowledge of the Divine counsels" (Plummer). See Lu 10:22; 15:7,10. Here the future tense occurs, "I will send" (αποστελω).

Some of them (εξ αυτων). No "some" (τινας) in the Greek, but understood. They will act as their fathers did. They will kill and persecute.