A.T. Robertson Commentary Mark 16:15

"And he said unto them, Go ye into all the world, and preach the gospel to the whole creation." — Mark 16:15 (ASV)

To the whole creation (παση τη κτισε). This commission in Mark is probably another report of the missionary Magna Charta in Mt 28:16-20 spoken on the mountain in Galilee. One commission has already been given by Christ (John 20:21–23). The third appears in Lu 24:44-49; Acts 1:3–8.