Charles Ellicott Commentary Daniel 2:43

"And whereas thou sawest the iron mixed with miry clay, they shall mingle themselves with the seed of men; but they shall not cleave one to another, even as iron doth not mingle with clay." — Daniel 2:43 (ASV)

Seed of men.— The great obscurity of this verse is partially cleared by a reference to Jeremiah 31:27. Daniel appears to be contrasting what man is endeavoring to accomplish by his own efforts with what the God of heaven (Daniel 2:44) will carry out. Man will form his plans for uniting the discordant parts of this empire, by encouraging marriages between the royal families that rule the various component kingdoms. (Daniel 11:17, Notes.)