Charles Ellicott Commentary Deuteronomy 28:27

"Jehovah will smite thee with the boil of Egypt, and with the emerods, and with the scurvy, and with the itch, whereof thou canst not be healed." — Deuteronomy 28:27 (ASV)

The botch of Egypt. —The “boil,” with which the Egyptians were plagued (Exodus 9:9 and following), is the same word. (See also 2 Kings 20:7; Job 2:7.) Rashi says of this boil, “It was very bad, being moist on the inside, and dry outside.” A learned Dalmatian Jew, with whom I have read this passage, tells me that he has seen many cases of this kind among the Hungarian and Polish Jews, and that it prevails among them, being traceable partly to their uncleanliness.

Emerods — i.e., hemorrhoids (as in 1 Samuel 5:6).

The scab. —In Leviticus 21:20; Leviticus 22:22, it is “scurvy.” It would make both a priest and an offering unclean, and unfit for the service of Jehovah.

The itch. —Here only. “A dry ulcer like a potsherd” (Rashi).

From which you cannot be healed. —Not that these afflictions are in themselves incurable, but that for those who contracted them, they would be incurable.