Charles Ellicott Commentary Deuteronomy 33:16

"And for the precious things of the earth and the fulness thereof, And the good will of him that dwelt in the bush. Let [the blessing] come upon the head of Joseph, And upon the crown of the head of him that was separate from his brethren." — Deuteronomy 33:16 (ASV)

The good will of him that dwelt in the bush —is a blessing peculiar to Moses. It contains an exquisite piece of interpretation. From the fact that Jehovah revealed Himself to Moses in a flame of fire in a bush, the man of God drew the thought that He presented Himself as dwelling in it; and thus he has provided God’s Church with this comfort for all ages: that His human temple, although it burns with fire, can never be consumed.

The last part of Deuteronomy 33:16 is taken directly from Genesis 49:26.

Separated from his brethren. —Hebrew, nâzîr. Is it altogether unreasonable to suppose that this particular feature in Joseph’s history, when he was sold into Egypt, and separated from his brethren, may be part of the meaning of “Nazarene” when applied to our Lord in Matthew 2:23?