Charles Ellicott Commentary Ezekiel 24:21

"Speak unto the house of Israel, Thus saith the Lord Jehovah: Behold, I will profane my sanctuary, the pride of your power, the desire of your eyes, and that which your soul pitieth; and your sons and your daughters whom ye have left behind shall fall by the sword." — Ezekiel 24:21 (ASV)

Profane my sanctuary. —Not merely by its destruction, but by the manner of its destruction, the Gentiles being allowed to enter its most sacred precincts, and carry off in triumph its sacred vessels and treasures. It was in the confidence that God would protect this that the last hope of the Jews lay; He tells them that He will Himself profane it.