Charles Ellicott Commentary Matthew 27:50

"And Jesus cried again with a loud voice, and yielded up his spirit." — Matthew 27:50 (ASV)

When he had cried again with a loud voice — We should remember the words that immediately preceded His last cry: It is finished (John 19:30) and Father, into Your hands I commend My spirit (Luke 23:46). These words expressed the fullness of peace and trust, and the sense of a completed work.

Crucifixion rarely ended as quickly as it did in this case. Those who have discussed the physical causes of our Lord's death—a subject perhaps not entirely suitable for discussion—have often ascribed it to a rupture of the heart's vessels. They connect this theory to the fact recorded in John 19:34 and to the "loud cry," which indicates the pangs of an intolerable anguish.

However, simple exhaustion resulting from the long vigil, the agony in the garden, the mocking, and the scourging would be an almost equally natural explanation.

Yielded up the ghost — A better translation is, yielded up His spirit. All four Evangelists agree in using this or a similar expression, instead of the simpler phrase, “He died.” It is as if they dwelt on the act as being, in some sense, voluntary, and connected it with the words in which He had commended His spirit to the Father (Luke 23:46).