Charles Ellicott Commentary Psalms 109:2

"For the mouth of the wicked and the mouth of deceit have they opened against me: They have spoken unto me with a lying tongue." — Psalms 109:2 (ASV)

Of the deceitful. —Properly, as in margin, of deceit; consequently, to make the two expressions alike, it is proposed to read, instead of “mouth of the wicked” (properly, of a wicked man), “mouth of wickedness.” In any case the best English equivalent will be, “a wicked mouth and a deceitful mouth.” “A blow with a word strikes deeper than a blow with a sword” (Whichcote).

Spoken against me. —Rather , talked with me.