Charles Ellicott Commentary Psalms 134:2

"Lift up your hands to the sanctuary, And bless ye Jehovah." — Psalms 134:2 (ASV)

Lift up your hands (see Note, Psalms 28:2) (in) the sanctuary.—The usual meaning would be to the sanctuary (see reference above), but since the servants of Jehovah are here addressed as standing in the sanctuary, this direction seems unreasonable. Render, therefore, in holiness, and compare lifting up holy hands (1 Timothy 2:8).