Charles Spurgeon Commentary Isaiah 44:25

"that frustrateth the signs of the liars, and maketh diviners mad; that turneth wise men backward, and maketh their knowledge foolish;" — Isaiah 44:25 (ASV)

This is what He does to those who boast and think that they know better than He does. But simple hearts, that will believe His Word, will know His will, and will grow wise unto salvation.