John Calvin Commentary 1 Thessalonians 2:15

"who both killed the Lord Jesus and the prophets, and drove out us, and pleased not God, and are contrary to all men;" — 1 Thessalonians 2:15 (ASV)

Who killed the Lord Jesus. Since those people had been distinguished by so many benefits from God, because of the glory of the ancient fathers, their very name held great authority for many. So that this pretense would not dazzle anyone's eyes, he strips the Jews of all honor, leaving them with nothing but odium and the utmost infamy.

“Look,” he says, “the virtues for which they deserve praise among the good and pious! — They killed their own prophets and finally the Son of God; they have persecuted me, his servant; they wage war against God; they are detested by the whole world; they are hostile to the salvation of the Gentiles; in short, they are destined for everlasting destruction.”

The question is raised: Why does he say that Christ and the prophets were killed by the same people? I answer that this refers to the entire body, for Paul means that there is nothing new or unusual in their resisting God; on the contrary, they are, in this way, filling up the measure of their fathers, as Christ says (Matthew 23:32).