John Calvin Commentary Acts 13:4

"So they, being sent forth by the Holy Spirit, went down to Seleucia; and from thence they sailed to Cyprus." — Acts 13:4 (ASV)

Being sent out by the Holy Ghost. There is no mention made here of the election made by the Church, because it was altogether a divine calling; the Church only received those who were offered by the hand of God. He says that they came first to Seleucia, which was a city of Syria. There was, indeed, a country of the same name; but it is more likely that Luke speaks of the city, which was not far from Cyprus by sea.