John Calvin Commentary Isaiah 24:9

"They shall not drink wine with a song; strong drink shall be bitter to them that drink it." — Isaiah 24:9 (ASV)

They shall not drink wine with a song. To drink wine is not in itself evil, because God has appointed it for human use; but here the Prophet describes the banquets of drunkards, which were full of licentiousness, songs, and insolence. Again, because they abused their enjoyment of plenty, he threatens them with scarcity, which people almost bring upon themselves when by their luxury they misuse the goodness of God.

Strong drink shall be bitter. He adds that if they drink wine, it will be “bitter” to them, because sorrow commonly deprives people of pleasure in both what they eat and what they drink. The meaning can be summarized as follows: “Though they have an abundance of wine, they will still be deprived of its use, because they will feel such sorrow that it will take away all pleasure in it.” “Strong drink shall be bitter;” that is, you shall no longer enjoy those pleasures and delights in which you have until now indulged.