John Calvin Commentary Jeremiah 49:33

"And Hazor shall be a dwelling-place of jackals, a desolation for ever: no man shall dwell there, neither shall any son of man sojourn therein." — Jeremiah 49:33 (ASV)

Here Jeremiah concludes his prophecy concerning the Kedareans; he says that their land would be deserted. The Prophets often use this manner of speaking: that the land, deserted by its inhabitants, would become the dwelling place of dragons. And this is more severe than when the land remains empty, for when dragons replace humans, it is a terrible thing.

Therefore, so that God’s judgment might make a stronger impression on people's feelings, the Prophets often declare that a deserted place would become the dwelling of dragons. He adds what means the same thing, A waste shall it be for an age: but עולם, oulam, means perpetuity. And it is added, Not dwell there shall a man, nor live there shall a son of man. There seems indeed to be an excess of words, for it would have been sufficient to say in one sentence that the land would be deserted and not inhabited.

But he first assigns it to dragons; then he adds that it would be a waste or solitude; and lastly, he says that no one would dwell there. Not only that, but having mentioned man, he adds the son of man. Some indeed think that by man the nobles are referred to, and that by the son of man, or Adam, we should understand the common people, the multitude. But as we have said elsewhere, this interpretation is too subtle. It is a repetition that increases the effect, though in the second clause he speaks more generally and expresses the thing more clearly, as if he had said that no one of the human race would become an inhabitant of that land.