John Calvin Commentary Matthew 10:11

"And into whatsoever city or village ye shall enter, search out who in it is worthy; and there abide till ye go forth." — Matthew 10:11 (ASV)

Inquire what person in it is worthy. Again, they might object that they would be deprived of the food to which they were entitled, because nobody would acknowledge them as laborers. But Christ also addresses this difficulty by ordering them to make inquiry what person in each city is worthy of the message of salvation. By these words, he instructs them to ask if there are any godly and upright men, who have some fear and reverence for God, and of whose readiness to receive instruction good hopes may be entertained, so that they may direct their labors chiefly to them. For, as they were not at liberty to remain long in any one place, it was proper to begin with those who were, in some respect, better prepared.

Remain there till you depart. This too relates to promptness: for if they had made a longer stay in any place, it would have been necessary to change their lodging, so that they might not be too burdensome to any individual. Therefore, when Christ commands them to remain in the house of the person who first receives them, till they depart to another city, he indicates that they must hurry, so that, after having published the Gospel in one city, they may immediately run to another.