John Calvin Commentary Psalms 110:5

"The Lord at thy right hand Will strike through kings in the day of his wrath." — Psalms 110:5 (ASV)

The Lord at your right hand. In these words, David celebrates the formidable nature of the power Christ possesses for the scattering and destruction of His enemies. Through this, he affirms that even though Christ is surrounded by bands of deadly foes, their malicious attempts will not prevent God from upholding the King whom He has established.

It is proper to consider the expression in the day of His wrath, which instructs us to patiently endure the cross if God, for a time, conceals Himself while the cruelty and fury of enemies prevail; for He knows well when the full and appropriate time arrives to execute vengeance upon them.

Next, David invests Christ with power over the nations and the people of uncircumcised lips. This means that Christ was not chosen King to reign only over the inhabitants of Judea, but also to keep distant nations under His sway, in agreement with what was declared concerning Him in Psalm 2:8.

Furthermore, because there would be many rebellious and disobedient people in all parts of the earth, as well as within the confines of Judea, David also refers to their destruction. He thus indicates that all who set themselves against Christ must be made to fall before Him, and their obstinacy will be subdued.