John Calvin Commentary Psalms 58:3

"The wicked are estranged from the womb: They go astray as soon as they are born, speaking lies." — Psalms 58:3 (ASV)

They are estranged, being wicked from the womb. To emphasize the severity of their character, he points to the fact that they were not recent sinners, but individuals born to commit sin. We see some people, whose disposition is otherwise not so depraved, who are drawn into evil ways through thoughtlessness, bad example, the enticement of their appetites, or similar circumstances; but David accuses his enemies of being imbued with wickedness from the womb, alleging that their treachery and cruelty were born with them.

We all come into the world stained with sin, possessing, as Adam’s descendants, an essentially depraved nature, and, in ourselves, incapable of aiming for anything good. However, there is a hidden restraint upon most people which prevents them from going to every extreme in wickedness.

The stain of original sin clings to all humanity without exception. Yet, experience proves that some are characterized by modesty and decency in outward behavior, that others are wicked but still within moderate limits, while a third class are so depraved in disposition as to be intolerable members of society.

Now, it is this excessive wickedness—so pronounced that it cannot escape condemnation even amid the general corruption of humanity—which David ascribes to his enemies. He brands them as monsters of iniquity.