John Gill Commentary 2 Corinthians 4:9

"pursued, yet not forsaken; smitten down, yet not destroyed;" — 2 Corinthians 4:9 (ASV)

Persecuted, but not forsaken
Pursued from place to place, and followed with menaces, curses, and reproaches; laid hold on, proscribed, imprisoned, and threatened with the severest tortures, and death itself; but our God never leaves us nor forsakes us; though we are followed close by evil men, and left by our friends, we are not forsaken of God:

cast down
we sometimes are, as an earthen vessel; (2 Corinthians 4:7) , which may be cast out of a man's hands, in order to be dashed to pieces; or as a man in wrestling, see (Ephesians 6:12) may be thrown to the ground by his antagonist, so we are sometimes foiled by sin, Satan, and the world:

but not destroyed ;
we are still safe in the hands of Christ, and are kept by the power of God; and, indeed, to what else can all this be ascribed? it is surprising that earthen vessels should bear and suffer so much, and not fall, or be dashed to pieces.