John Gill Commentary Genesis 27:22

"And Jacob went near unto Isaac his father. And he felt him, and said, The voice is Jacob`s voice, but the hands are the hands of Esau." — Genesis 27:22 (ASV)

And Jacob went near to Isaac his father Boldly and without trembling; which he could the better do, as his father could not see him, and so not capable of discerning any change in his countenance or outward behaviour: and he felt him; some parts of his body, especially his hands: and said, the voice [is] Jacob's voice; very like it, as if it was the same, as indeed it was: but the hands [are] the hands of Esau; are like them, being hairy as they; or, as the Targums of Jonathan and Jerusalem, "the feeling of the hands is as the feeling of the hands of Esau;" they feel like them.