John Gill Commentary Isaiah 10:25

"For yet a very little while, and the indignation [against thee] shall be accomplished, and mine anger [shall be directed] to his destruction." — Isaiah 10:25 (ASV)

For yet a very little while Within a few days; for in a very short time after Sennacherib was come up against Jerusalem his army was destroyed by an angel.

and the indignation shall cease The indignation of the Lord against his people Israel, shown by bringing the Assyrian monarch against them, of which he was the staff or instrument, (Isaiah 10:5).

and mine anger in their destruction Not in the destruction of the Jews, but the Assyrians: the sense is, that the anger of God towards the people of the Jews for the present should be discontinued, when the Assyrian army was destroyed.

The Targum says: "for yet a very little while, and the curses shall cease from you of the house of Jacob; and mine anger shall be upon the people that work iniquity, to destroy them;" that is, the Assyrians.