John Gill Commentary Isaiah 2:15

"and upon every lofty tower, and upon every fortified wall," — Isaiah 2:15 (ASV)

And upon every high tower, and upon every fenced wall .
] Which may signify everything that serves to support and defend the antichristian hierarchy, particularly the secular powers. The Targum paraphrases it, and upon all that dwell in a high tower, and upon all that reside by a fortified wall.''