John Gill Commentary Isaiah 45:10

"Woe unto him that saith unto a father, What begettest thou? or to a woman, With what travailest thou?" — Isaiah 45:10 (ASV)

Woe to him that says to his father, what you beget ? &c.] That quarrels with him, and complains of him, because he was not of the other sex, or not so wise, or so rich, or so handsome, as others: or to the woman ; disdaining to call her mother: what have you brought forth ? equally as absurd and impious it was in the Jews to quarrel with Christ for his conversation with sinners, and the reception of them; or for the regeneration of such persons; or to find fault with God for the conversion of the Gentiles, and resent it, and be angry at it, as they were; see (Romans 10:19Romans 10:20) (1 Thessalonians 2:16) .