John Gill Commentary Isaiah 63:6

"And I trod down the peoples in mine anger, and made them drunk in my wrath, and I poured out their lifeblood on the earth." — Isaiah 63:6 (ASV)

And I will tread down the people in my anger
(See Gill on Isaiah 63:3), and make them drunk in my fury ;
or with it ^F19 the wrath of God is signified by a cup, which he gives wicked men to drink, and which is an inebriating one to them, (Psalms 75:8) (Isaiah 51:17–23) (Jeremiah 25:15) , and here it signifies the cup of the wine of the fierceness of God's wrath, which shall be given to mystical Babylon, to antichrist and his followers, (Revelation 14:10) (16:19) : and I will bring down their strength to the earth ;
their strong kingdoms, fortified cities, and mighty men, their wealth and riches, of which they boasted, and in which they trusted; see (Isaiah 26:5) . The eighteenth chapter of the Revelation is a commentary on these words.

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FOOTNOTES:

• F19: (ytmxb) "excandescentia mea", Junius & Tremellius; "aestu meo", Cocceius; so Gataker.