John Gill Commentary Isaiah 64:8

"But now, O Jehovah, thou art our Father; we are the clay, and thou our potter; and we all are the work of thy hand." — Isaiah 64:8 (ASV)

But now, O Lord, you are our father. Notwithstanding all that we have done against you, and you have done to us, the relation of a father continues; you are our Father by creation and adoption; as he was in a particular manner to the Jews, to whom belonged the adoption; and therefore this relation is pleaded, that mercy might be shown them; and so the Targum, "and you, Lord, your mercies towards us 'are' many (or let them be many) as a father towards 'his' children."

We are the clay, and you our potter: respecting their original formation out of the dust of the earth; and so expressing humility in themselves, and yet ascribing greatness to God, who had curiously formed them, as the potter out of the clay forms vessels for various uses: it may respect their formation as a body politic and ecclesiastic, which arose from small beginnings, under the power and providence of God; see (Deuteronomy 32:6).

and we all are the work of your hand; and therefore regard us, and destroy us not; as men do not usually destroy their own works: these relations to God, and circumstances in which they were as creatures, and as a body civil and ecclesiastic, are used as arguments for mercy and favour.