John Gill Commentary Jeremiah 21:10

"For I have set my face upon this city for evil, and not for good, saith Jehovah: it shall be given into the hand of the king of Babylon, and he shall burn it with fire." — Jeremiah 21:10 (ASV)

For I have set my face against this city
Or "my fury", as the Targum; their sins had provoked the eyes of his glory; he was wroth with them, and determined to cut them off; his mind was set against them, and upon their ruin; and there was no turning him from it:

for evil, and not for good, saith the Lord ;
to bring the evil of punishment upon them for the evil of their sins, and not do any good unto them, they were so ill deserving of:

it shall be given into the hand of the king of Babylon ;
come under his power and dominion, by the will of the Lord; for it was he that gave it into his hands, because of the sins of the inhabitants of it:

and he shall burn it with fire ;
as he did, both the house of the Lord in it, the temple, the king's house or palace, the stately houses of the princes and nobles, and even the houses of all the people; see (Jeremiah 52:13) .