John Gill Commentary Jeremiah 49:15

"For, behold, I have made thee small among the nations, and despised among men." — Jeremiah 49:15 (ASV)

For, lo, I will make you small among the Heathen
Or, "I have given you", or "made you" ^F13 ; as if it respected what Edom was at first, a people few in number, and their country not large, as Aben Ezra and Kimchi, and after them Abarbinel: but it rather intends what Edom should be ^F14 ; and which was the reason of gathering the Chaldeans against them, to reduce their number, weaken their strength, and destroy their substance, and so make them a small, feeble, and contemptible people; as follows: [and] despised among men :
for the fewness of their men, the desolation of their country, the consumption of their wealth and riches, their poverty and meanness; see (Obadiah 1:2) .

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FOOTNOTES:

• F13: (Kyttn) "posui", Munster; "reddidi", Piscator; dedi", V. L. Cocceius, Schmidt.
• F14: Dabo, Pagninus, Montanus. So Ben Melech.