John Gill Commentary Jeremiah 49:22

"Behold, he shall come up and fly as the eagle, and spread out his wings against Bozrah: and the heart of the mighty men of Edom at that day shall be as the heart of a woman in her pangs." — Jeremiah 49:22 (ASV)

Behold, he shall come up, and fly as the eagle The Targum is, ``behold, as an eagle comes up and flies, so shall a king come up with his army;'' the king of Babylon with his army, compared to an eagle for his swiftness and voraciousness, as before to a lion for his strength and fierceness:

and spread his wings over Bozrah besiege that city, invest it, and seize upon it; very fitly are the wings of an army expressed by the wings of this bird, denoting both their extent and force; the same is said concerning Moab, (Jeremiah 48:40);

and at that day shall the heart of the mighty men of Moab be as the
heart of a woman in her pangs when just ready to be delivered; not only weak and timorous, but full of anguish, and: quite dispirited; (See Gill on Jeremiah 48:41).