John Gill Commentary Jeremiah 51:23

"and with thee will I break in pieces the shepherd and his flock; and with thee will I break in pieces the husbandman and his yoke [of oxen]; and with thee will I break in pieces governors and deputies." — Jeremiah 51:23 (ASV)

And I will also break in pieces with you the shepherd and his
flock
Or, have broken; which Abarbinel thinks respects the Arabians particularly, who were shepherds, and dwelt in tents; but it rather signifies shepherds and their flocks in general; who were killed or scattered wherever his armies came, which spared none, even the most innocent and useful, and though unarmed: and with you will I break in pieces the husbandman and his yoke of
oxen ;
with which he ploughed his ground: signifying by this, as well as the former, that those were not spared, by which kingdoms were supported and maintained, as shepherds and husbandmen: and with you will I break in pieces captains and rulers ;
by whom kingdoms and states are governed and protected.